Tylenol #3
| Tylenol #3 | |
|---|---|
| DOSAGE | 1 or 2 TAB PO q4hr to q6hr |
| GENERIC | 30mg codeine, 300mg acetaminophen |
| SIZE | 12-24 Tabs |
| INDICATIONS | management of mild to moderate pain, where treatment with an opioid is appropriate and for which alternative treatments are inadequate. |
| MECHANISM OF ACTION | Opioid agonist, antitussive Analgesic, antipyretic |
| MICROBIOLOGY | Codeine: Opioid agonist; analgesia; blocks pain impulse generation and inhibits ascending pain pathways, thus altering the perception and response to pain; inhibits cough by acting centrally in the medulla; causes CNS depression |
| Acetaminophen: Nonopioid, nonsalicylate analgesic; may work peripherally to block pain impulse generation; acts on hypothalamus to produce antipyresis | |
| CONTRAINDICATIONS & WARNINGS | Contraindicated in patients <12 years of age. Post-operative management in children younger than 18 years of age following tonsillectomy and/or adenoidectomy |
| PEDIATRIC USE | Contraindicated in patients <12 years of age |
| PREGNANCY | Category C There are no adequate and well-controlled studies in pregnant women |
| NOTE | Schedule III |