Timolol | Other Derivatives

Timolol

Generic:

  • Timolol maleate 0.5%
  • Betimol (timolol hemihydrate 0.25%, 0.5%) - different chemical structure
  • Istalol (timolol maleate 0.5%) - dosed qAM
  • Timoptic Ocudose (timolol maleate 0.25%, 0.5%) - ocudose dispenser  
  • Timoptic XE (timolol maleate 0.25, 0.5%) - gel forming solution
Timolol | Other Derivatives
DOSAGE 1gtt BID. Clinically, 1gtt qAM is common.
GENERIC Timolol maleate 0.5% | Betimol (timolol hemihydrate 0.25%, 0.5%) - different chemical structure | Istalol (timolol maleate 0.5%) - dosed qAM | Timoptic Ocudose (timolol maleate 0.25%, 0.5%) - ocudose dispenser | Timoptic XE (timolol maleate 0.25, 0.5%) - gel forming solution
SIZE 5mL, 10mL, 15mL
INDICATIONS Reduces intraocular pressure (IOP)
MECHANISM OF ACTION non-selective beta-adrenergic antagonist
MICROBIOLOGY The predominant mechanism of ocular hypotensive action of topical beta-adrenergic blocking agents is likely due to a reduction in aqueous humor production.
CONTRAINDICATIONS & WARNINGS Patients with overt heart failure, cardiogenic shock, sinus bradycardia, second- or third-degree atrioventricular block, bronchial asthma or history of bronchial asthma, or severe chronic obstructive pulmonary disease, or hypersensitivity to any component of this product.
PEDIATRIC USE Safety and efficacy in pediatric patients have not been established.
PREGNANCY Category C
NOTE