Pilocarpine HCl

Pilocarpine HCl
		DOSAGE	1 gtt qD, up to QID
		GENERIC	Pilocarpine HCl 1%, 2%, 4%
		SIZE	15 mL
		INDICATIONS	Reduction of elevated intraocular pressure (IOP)
		MECHANISM OF ACTION	Increase in outflow of aqueous
		MICROBIOLOGY	Pilocarpine contracts the ciliary muscle, causing increased tension on the scleral spur and opening of the trabecular meshwork spaces to facilitate outflow of aqueous humor. Outflow resistance is reduced, lowering intraocular pressure (IOP).
		CONTRAINDICATIONS & WARNINGS	None, but pilocarpine is not routinely used due to ADR such as increased risk for uveitis, retina detachment, miosis-induced angle closure, headache
		PEDIATRIC USE	In children under 2 years of age, one drop of pilocarpine hydrochloride ophthalmic solution 1% should be applied topically in the eye(s) three times daily. Children 2 years of age and over should be dosed as for adults.
		PREGNANCY	Pregnancy Category C
		NOTE	Sometimes used before laser surgery \| Pilocarpine is not routinely used due to ADR such as increased risk for uveitis, retina detachment, miosis-induced angle closure, headache
		NOTE	Vuity (1.25% Pilocarpine) is a part of the Cholinergic Agonists class and treats Presbyopia.