Physiologic Anisocoria

Physiologic Anisocoria
		SYMPTOMS	Asymptomatic
		SIGNS	Anisocoria that is equal in light and dark (The anisocoria is usually 1mm or less), Normal light response, Normal near response
		SIGNS	No other neurological signs
		WORK-UP	Pupils \| EOMs \| Full eye exam with dilation \| Ptosis testing
		TREATMENT	No treatment needed
		FOLLOW-UP	Monitor in 1 year
		ADDITIONAL LAB \| TESTS	None
		ETIOLOGY	Thought to be due to unbalanced supranuclear inhibition of the parasympathetic nuclei in the midbrain
		DIFFERENTIAL DX	Horner’s syndrome, Adie’s syndrome, Cranial nerve III palsy with pupil involvement
		NOTES	About 20% of the population has physiologic anisocoria
			The amount of anisocoria may change throughout the day and may even show reversal