Klarity-C (Pres-free)
| Klarity-C (Pres-free) | |
|---|---|
| DOSAGE | 1 gtt BID (12 hours apart) |
| GENERIC | cyclosporine 0.1% |
| SIZE | 5.5mL bottle (10 bottles per box) |
| INDICATIONS | Indicated to increase tear production where tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca. |
| MECHANISM OF ACTION | peptide immunosuppressant |
| MICROBIOLOGY | Calcineurin inhibitor, modulates T-cell function and increases goblet cell density. |
| CONTRAINDICATIONS & WARNINGS | 17% to 22% report pain or burning on instillation with cyclosporine | Active ocular infections and hypersensitivity to any ingredients |
| PEDIATRIC USE | Safety and efficacy not established in pediatric patients. Transplant recipients as young as one year of age have received cyclosporine with no unusual adverse effects. |
| PREGNANCY | Category C | Embryo- and fetotoxic in rats and rabbits following oral administration at 5000 and 32000 times the normal numan dose. |
| NOTE | 503-B preparation. Not FDA approved. Unpreserved emulsion contains chondroitin sulfate, glycerin, and other lubricants. It is speculated that the chondroitin could benefit corneas stressed with contact lens wear |