Iopidine
| Iopidine | |
|---|---|
| DOSAGE | 1 gtt TID. Clinically, BID is used most commonly |
| GENERIC | Apraclonidine 0.5%, 1% |
| SIZE | 5mL, 10mL |
| INDICATIONS | Reduction of elevated intraocular pressure (IOP) in patients with glaucoma. Also indicated to control or prevent post-surgical elevations in IOP that occur in patients after argon laser trabeculoplasty, argon laser iridotomy or Nd:YAG posterior capsulotomy |
| MECHANISM OF ACTION | alpha-2 agonist |
| MICROBIOLOGY | The precise mechanism of the ocular hypotensive action of IOPIDINE 1% Ophthalmic Solution is not completely established at this time. Aqueous fluorophotometry studies in man suggest that its predominant action may be related to a reduction of aqueous formation. |
| CONTRAINDICATIONS & WARNINGS | Patients receiving monoamine oxidase inhibitor therapy and for patients with hypersensitivity to any component of this medication or to clonidine. |
| PEDIATRIC USE | Safety and effectiveness in pediatric patients have not been established. |
| PREGNANCY | Category C Apraclonidine HCl has been shown to have an embryocidal effect in rabbits |
| NOTE | Rarely used in glaucoma. Sometimes used for ocular laser procedures |