Iopidine

Iopidine

Generic: Apraclonidine 0.5%, 1%

Iopidine
DOSAGE 1 gtt TID. Clinically, BID is used most commonly
GENERIC Apraclonidine 0.5%, 1%
SIZE 5mL, 10mL
INDICATIONS Reduction of elevated intraocular pressure (IOP) in patients with glaucoma. Also indicated to control or prevent post-surgical elevations in IOP that occur in patients after argon laser trabeculoplasty, argon laser iridotomy or Nd:YAG posterior capsulotomy
MECHANISM OF ACTION alpha-2 agonist
MICROBIOLOGY The precise mechanism of the ocular hypotensive action of IOPIDINE 1% Ophthalmic Solution is not completely established at this time. Aqueous fluorophotometry studies in man suggest that its predominant action may be related to a reduction of aqueous formation.
CONTRAINDICATIONS & WARNINGS Patients receiving monoamine oxidase inhibitor therapy and for patients with hypersensitivity to any component of this medication or to clonidine.
PEDIATRIC USE Safety and effectiveness in pediatric patients have not been established.
PREGNANCY Category C Apraclonidine HCl has been shown to have an embryocidal effect in rabbits
NOTE Rarely used in glaucoma. Sometimes used for ocular laser procedures