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DOSAGE
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1-2 gtts BID beginning the day after surgery. Continue for 2 weeks post-op.
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Taper if used off label for extended period.
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INDICATIONS
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INVELTYS is a corticosteroid indicated for the treatment of post-operative inflammation and pain following ocular surgery.
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MECHANISM OF ACTION
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Ester based "soft" steroid (micro-particle)
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MICROBIOLOGY
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Corticosteroids inhibit the inflammatory response to a variety of inciting agents and probably delay or slow healing. They inhibit the edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, fibroblast proliferation, deposition of collagen, and scar formation associated with inflammation. While glucocorticoids are known to bind to and activate the glucocorticoid receptor, the molecular mechanisms involved in glucocorticoid/glucocorticoid receptor-dependent modulation of inflammation are not clearly established. However, corticosteroids are thought to inhibit prostaglandin production through several independent mechanisms.
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CONTRAINDICATIONS & WARNINGS
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INVELTYS is contraindicated in most viral diseases of the cornea and conjunctiva including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also in mycobacterial infection of the eye and fungal diseases of ocular structures.
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PEDIATRIC USE
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Safety and effectiveness in pediatric patients have not been established.
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PREGNANCY
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INVELTYS is not absorbed systemically following topical ophthalmic administration and maternal use is not expected to result in fetal exposure to the drug.
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NOTE
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Intraocular Pressure (IOP) Increase, Cataracts, Delayed Healing, Bacterial Infections, Viral Infections, Fungal Infections, Risk of Contamination, Remove CL prior to instill
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Enhanced penetration due to micro-particle delivery and proprietary coating. 0.01% BAK preserved.
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