Herpes Simplex Keratitis

Herpes Simplex Keratitis
SYMPTOMS Pain | Photophobia | Tearing | Blurry vision
SIGNS Injection | Tearing | Vesicles/dendrites | Possible geographic ulcer
WORK-UP Thorough history. Slit lamp examination
Topical antivirals: Zirgan 1 gtt 5x/day | Trifluridine 1% 9x/day
Oral antivirals: Acyclovir 400 mg 5x/day x 7-10 days | Valacyclovir 500 mg tid x 7-10 days | Famciclovir 250 mg tid x 7-10 days
FOLLOW-UP Every few days
ADDITIONAL LAB | TESTS NaFl stain | Lissamine green stain | Rose bengal stain | Cornea esthesiometry | Giemsa stain is rarely utilized
ETIOLOGY Herpes simplex virus
DIFFERENTIAL DX Herpes zoster ophthalmicus | Acanthamoeba keratitis | Thygeson’s SPK | Staphylococcal marginal keratitis | Recurrent corneal erosion

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