Giant Papillary Conjunctivitis (GPC)

Giant Papillary Conjunctivitis (GPC)
SYMPTOMS Mucous discharge | Itching | Contact lens discomfort
SIGNS Mucous discharge | Giant papillae (superior tarsal plate)
WORK-UP Thorough history and slit lamp examination with upper lid eversion
TREATMENT Discontinue contact lens wear, topical steroid (Pred Forte 1% or Lotemax 1 gtt qid) | Topical allergy eye drops are minimally effective, especially if significant GPC is present) | If contact lens wear is to be resumed, switch to a daily disposable modality
FOLLOW-UP 2-4 weeks during treatment
ADDITIONAL LAB | TESTS None
ETIOLOGY Contact lens use - specifically poor hygiene and habits | GPC can also be caused by an ocular prosthesis.
DIFFERENTIAL DX Allergic conjunctivitis | EKC | VKC | Dry eye syndrome
NOTES Severe cases of GPC may take months to significantly improve

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