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SIGNS
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Guttae | Stromal edema | Descemet folds | Epithelial bullae | Scarring in advanced cases
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WORK-UP
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Thorough history | Slit lamp examination | Endothelial cell count (specular microscopy) | Pachymetry
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TREATMENT
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Muro 128 (sodium chloride 5%) drops and/or ointment | Endothelial keratoplasty
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FOLLOW-UP
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Annually if mild | 3-6 months if advanced
|
|
ADDITIONAL LAB | TESTS
|
Endothelial cell count (specular microscopy) | Pachymetry
|
|
ETIOLOGY
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There is a genetic predisposition (autosomal dominant)
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DIFFERENTIAL DX
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Congenital hereditary endothelial dystrophy | ICE syndrome | Posterior polymorphous corneal dystrophy | Bullous keratopathy
|
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NOTES
|
There are a variety of endothelial keratoplasty techniques currently available
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