Iris

Iris melanoma SYMPTOMS No symptoms SIGNS Raised iris lesion, diffuse or circumscribed, pigmented or nonpigmented | Feeder vessel | Possible IOP increase | Possible hyphema WORK-UP Thorough history | Slit lamp examination | DFE | Gonioscopy | UBM (gold standard) or AS-OCT to image lesion TREATMENT Close observation (every few months) | Surgical resection with…

Iris cyst SYMPTOMS No symptoms SIGNS Raised iris lesion may appear dark without demonstrating transillumination or clear with transillumination WORK-UP Thorough history and slit lamp examination | UBM (gold standard) or AS-OCT to image lesion TREATMENT Observation with photodocumentation and/or UBM | Laser treatment (photodisruption and photocoagulation) or surgical excision may be indicated in more…

Iris nevus SYMPTOMS No symptoms SIGNS Hyperpigmented (sometimes hypopigmented) iris lesion – could be diffuse or circumscribed WORK-UP Thorough history. Slit lamp examination TREATMENT Observation with photodocumentation FOLLOW-UP Annually to assess malignancy risk ADDITIONAL LAB | TESTS Photodocumentation ETIOLOGY Increased melanocytes | There is an association with UV exposure DIFFERENTIAL DX Iris melanoma | Iris…