Bromsite (soln)
| Bromsite (soln) | |
|---|---|
| DOSAGE | 1gtt to affected eye BID (AM/PM) x beginning 1 day prior to surgery, the day of surgery, and 14 days post surgery. |
| GENERIC | Bromfenac 0.075% |
| SIZE | 5mL |
| INDICATIONS | BromSite is a nonsteroidal anti-inflammatory drug (NSAID) indicated for the treatment of postoperative inflammation and prevention of ocular pain in patients undergoing cataract surgery |
| MECHANISM OF ACTION | NSAID (COX inhibitor) |
| MICROBIOLOGY | Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) that has anti-inflammatory activity. The mechanism of its action is thought to be due to its ability to block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. |
| CONTRAINDICATIONS & WARNINGS | Hypersensitivity to any ingredient in this formulation |
| PRED-G® suspension is also contraindicated in individuals with known or suspected hypersensitivity to any of the ingredients of this preparation or to other corticosteroids. | |
| PEDIATRIC USE | Safety and efficacy in pediatric patients below the age of 18 years have not been established. |
| PREGNANCY | Category C |
| Prednisolone has been shown to be teratogenic in mice when given in doses 1-10 times the human ocular dose. Dexamethasone, hydrocortisone and prednisolone were applied to both eyes of pregnant mice five times per day on days 10 through 13 of gestation. A significant increase in the incidence of cleft palate was observed in the fetuses of the treated mice. There are no adequate well-controlled studies in pregnant women. PRED-G® suspension should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. | |
| NOTE | Formulated in Durasite vehicle |