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DOSAGE
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Seasonal Allergic Conjunctivitis: 1 gtt QID for ocular itching
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Post-Op Inflammation: 1 gtt QID in operated eye (or PRN for pain/burning/stinging) x 4 days
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GENERIC
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ketorolac tromethamin 0.5%
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INDICATIONS
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ACULAR LS® ophthalmic solution is indicated for the reduction of ocular pain and burning/stinging following corneal refractive surgery.
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MECHANISM OF ACTION
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NSAID (Non-selective COX inhibitor)
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MICROBIOLOGY
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Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug which, when administered systemically, has demonstrated analgesic, anti-inflammatory, and anti-pyretic activity. The mechanism of its action is thought to be due to its ability to inhibit prostaglandin biosynthesis.
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CONTRAINDICATIONS & WARNINGS
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Delayed Healing, Epithelial breakdown, corneal thinning, corneal erosion, corneal ulceration or corneal perforation possible in susceptible patients.
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Hypersensitivity to any of the ingredients in the formulation. Possible cross-sensitivity to acetylsalicylic acid, phenylacetic acid derivatives, and other nonsteroidal anti-inflammatory agents.
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PEDIATRIC USE
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Safety and efficacy in pediatric patients below the age of 3 have not been established.
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PREGNANCY
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There are no adequate or well-controlled studies with ACULAR LS® in pregnant women. No evidence of teratogenicity has been observed in rats or rabbits with ACULAR LS® at clinically relevant doses.
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NOTE
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Typically used instead of pressure patch and cycloplegia to control pain of corneal abrasion.
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All topical nonsteroidal anti-inflammatory drugs (NSAIDs) may slow or delay healing. Remove Contact lens prior to use
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Acular LS 0.40% LS: "LS" = Low Strength reformulation to reduce sting, compared to Acular 0.50%
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