Acanthamoeba Keratitis

Acanthamoeba Keratitis
		SYMPTOMS	Pain (usually severe) \| Photophobia \| Blurry vision
		SIGNS	Injection \| Epitheliopathy \| Corneal haze \| Ring-shaped infiltrate \| Anterior chamber cells/flare \| Hypopyon
		WORK-UP	Thorough history and slit lamp examination \| Culture and possible corneal biopsy \| Confocal biomicroscopy may be used
		TREATMENT	Discontinue contact lens wear (if applicable) \| A combination of biguanides (PHMB, chlorhexidine), diamidines (propamidine-isethionate), antibiotics and antifungals \| Oral analgesics (acetaminophen, ibuprofen, possible narcotic agents)
		FOLLOW-UP	Daily
		ADDITIONAL LAB \| TESTS	Culture \| Corneal biopsy \| Confocal biomicroscopy
		ETIOLOGY	Acanthamoeba
		DIFFERENTIAL DX	Herpes simplex keratitis \| Herpes zoster ophthalmicus \| Recurrent corneal erosion
		NOTES	Ask patients about contact lens wear, specifically rinsing/cleaning with tap water and/or swimming